9Jan/10Off
Pill Drug
Does freezing a prescription pill or other drug likely make it ineffective?
I left several prescriptions and over-the-counter medicines (ibuprofen, nyquil, albuterol inhaler) in a car for several days in single digit (8 F) cold-as-butt north dakota temeratures. Most things say "Store between 15-30 C or 59-86 F", but does it really do anything to freeze this stuff? Or are these just idle threats from the manufactures to cover their asses? Or could are the chemical compositions of these drugs likely to change? Thanks!
I doubt those would be damaged.
I think the main concern of the pharmaceuticals is to limit the damage that frozen water-ice crystals may cause to the individual molecules of the medications, but if they were in relatively air-tight containers they should be okay.
Maintaining the temperature relatively constant would reduce the chance of some cooler-prefering bacteria or mold growing on the tablets which sometimes contains sugar, I think.
The inhaler, I wouldn't know, except to say that as a child I frequently used inhalers on winter campouts in Massachusetts where our butts froze, too!
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